Hemophilia Research Today is a free monthly online journal that collates and summarizes the latest research about Hemophilia, including details on genetics, causes, symptoms, blood transfusion.

The safety and efficacy of enfuvirtide therapy for HIV infection in patients with hemophilia: a case series.

Polizzotto MN, Street AM, Wright E

Department of Haematology, The Alfred Hospital, Melbourne, Australia.

The treatment of patients with human immunodeficiency virus (HIV) infection and hemophilia involves unique challenges that may be addressed with novel antiretroviral classes. We describe the safety and efficacy of enfuvirtide therapy in 4 patients with severe hemophilia A. Although local skin reactions were common, neither local nor systemic bleeding worsened. Three patients achieved undetectable HIV loads with enfuvirtide salvage regimens.

Published 19 July 2007 in Clin Infect Dis, 45(4): e39-41.
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