Hemophilia Research Today is a free monthly online journal that collates and summarizes the latest research about Hemophilia, including details on genetics, causes, symptoms, blood transfusion.

Acquired factor VIII inhibitor presenting as macular haemorrhage.

Hon C, Liu H, Chan J

Department of Ophthalmology, Pamela Youde Nethersole Eastern Hospital, Hong Kong. honc@ha.org.hk

We report a rare case of idiopathic acquired factor VIII inhibitor in an 80-year old Chinese man presented as sudden onset of monocular blindness because of macular haemorrhage. This was complicated by painful glaucoma that did not respond to medical treatment. The patient died of cerebral haemorrhage shortly afterwards. Most cases of reported intraocular bleeding in acquired haemophiliacs are iatrogenic because of intraocular operations in undiagnosed cases, and spontaneous intraocular haemorrhage has never been reported. The literature reports of intraocular bleeding in hereditary and acquired haemophilia cases are summarized.

Published 6 April 2005 in Haemophilia, 11(2): 164-6.
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